Description

Estra-1,3,5(10)-Triene-3,17Alpha-Diol 3-Benzoate is a high-purity steroid derivative, specifically the 3-benzoate ester of estradiol. This compound is valued for its role as a key pharmaceutical intermediate and reference standard in research and development. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis and quality control of steroidal APIs and other advanced molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroidal active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in laboratories.
• Biochemical Research: Serves as a precursor or standard in studies involving estrogen receptors, hormone metabolism, and endocrine system research.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of specialized steroid derivatives for various experimental and industrial applications.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17Alpha-Diol 3-Benzoate
CAS No.	6045-53-0
Molecular Formula	C25H28O3
Molecular Weight	376.49 g/mol
Synonyms	Estradiol 3-Benzoate; 17β-Estradiol 3-Benzoate; Estra-1,3,5(10)-triene-3,17β-diol 3-benzoate; 3-Benzoyloxyestra-1,3,5(10)-trien-17β-ol; NSC 57153; Benzoic acid, (17β)-estra-1,3,5(10)-triene-3,17-diol 3-ester
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Triene-3,17Alpha-Diol 3-Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for use as a pharmaceutical intermediate. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.