Description

2-Iodopyridine-3-Carboxylic Acid is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an iodine substituent, makes it a valuable precursor for constructing complex molecules through cross-coupling and functional group interconversion. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and polymers.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Fine Chemical Production: Intermediate for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Iodopyridine-3-Carboxylic Acid
CAS No.	6042-35-9
Molecular Formula	C6H4INO2
Molecular Weight	249.01 g/mol
Synonyms	3-Carboxy-2-iodopyridine; 2-Iodo-3-pyridinecarboxylic Acid; 2-Iodonicotinic Acid; 2-Iodo-3-carboxypyridine; 3-Pyridinecarboxylic Acid, 2-iodo-; 2-Iodopyridine-3-carboxylic acid; 2-Iodo-3-pyridylcarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Iodopyridine-3-Carboxylic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.