Description

Methyl 4-Bromocrotonate is a versatile brominated ester building block used in advanced organic synthesis. This compound matters as a key intermediate for introducing functionalized crotonate moieties into target molecules, enabling the construction of complex chemical architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as Michael additions, cyclization reactions, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical intermediate in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Key building block for agrochemical research, particularly in creating new fungicides and herbicides.
• Versatile electrophile in organic synthesis for Michael addition reactions.
• Precursor in material science for the development of functional polymers and specialty monomers.
• Intermediate for synthesizing complex natural product analogs and fine chemicals.
• Use in cross-coupling reactions (e.g., Suzuki, Heck) to create more complex molecular structures.

Basic Information

Product Name	Methyl 4-Bromocrotonate
CAS No.	6000-00-6
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	Methyl (E)-4-Bromocrotonate; Methyl (E)-4-Bromo-2-butenoate; 4-Bromocrotonic Acid Methyl Ester; (E)-Methyl 4-bromobut-2-enoate; 2-Butenoic acid, 4-bromo-, methyl ester, (E)-; Methyl trans-4-bromocrotonate; Bromocrotonic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromocrotonate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 95.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.