Description

2,3,5-Collidine CAS NO 695-98-7 is a high-purity alkylated pyridine derivative, valued as a versatile intermediate and specialty base in advanced organic synthesis. Its unique steric and electronic properties make it an essential reagent for facilitating challenging chemical transformations and modulating reaction pathways. This compound is primarily sought by the pharmaceutical, agrochemical, and fine chemical industries for applications in catalysis, ligand synthesis, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Synthesis: Used as a precursor for creating specialized ligands and organocatalysts in asymmetric synthesis.
• Agrochemical Production: Serves as an intermediate in the manufacture of advanced pesticides and herbicides.
• Fine Chemical Synthesis: Employed as a base or directing agent in multi-step organic synthesis for high-value specialty chemicals.
• Research & Development: A valuable reagent in academic and industrial R&D labs for methodological development and scale-up studies.
• Coordination Chemistry: Utilized in the preparation of metal-organic frameworks (MOFs) and other coordination complexes.

Basic Information

Product Name	2,3,5-Collidine
CAS No.	695-98-7
Molecular Formula	C8H11N
Molecular Weight	121.18 g/mol
Synonyms	2,3,5-Trimethylpyridine; Asym-Collidine; 2,3,5-Trimethylpyridine; 3,5,6-Trimethylpyridine; NSC 9378; UNII-7K5F8V7318; α,α',β-Collidine; asym-Trimethylpyridine
EINECS	211-792-8

Quality Control

Our 2,3,5-Collidine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and the material is suitable for use in regulated environments. Comprehensive testing, including identity confirmation, purity assay, and impurity profiling, is performed. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	0.92 - 0.94 g/mL
Refractive Index (n20D)	1.498 - 1.502

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.