Description

n-(Trifluoroacetyl)-L-Aspartic Acid Dimethyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled introduction of L-aspartic acid motifs into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptides, peptidomimetics, and other bioactive compounds.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of peptides containing aspartic acid residues.
• Pharmaceutical Research: Used as a chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation Chemistry: Employed in the preparation of modified biomolecules and chemical probes for biochemical studies.
• Agrochemical Development: Serves as a building block for synthesizing advanced, chiral compounds with potential biological activity.
• Material Science: Can be utilized in the synthesis of specialized polymers and functional materials requiring precise stereochemistry.

Basic Information

Product Name	n-(Trifluoroacetyl)-L-Aspartic Acid Dimethyl Ester
CAS No.	688-09-5
Molecular Formula	C9H10F3NO6
Molecular Weight	285.17 g/mol
Synonyms	L-Aspartic acid, N-(trifluoroacetyl)-, dimethyl ester; (2S)-2-[(Trifluoroacetyl)amino]butanedioic acid dimethyl ester; N-TFA-L-Aspartic acid dimethyl ester; Dimethyl (2S)-2-[(2,2,2-trifluoroacetyl)amino]succinate; N-Trifluoroacetyl-L-aspartic acid dimethyl ester; N-(Trifluoroacetyl)-L-aspartic acid dimethyl ester; N-[(Trifluoroacetyl)-L-aspartic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-L-Aspartic Acid Dimethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.