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Diethyl Bromomalonate CAS NO 685-87-0


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CAS No.:685-87-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diethyl Bromomalonate is a versatile brominated malonic ester derivative, serving as a critical synthetic building block in organic chemistry. Its high reactivity, particularly in nucleophilic substitution and carbon-carbon bond-forming reactions, makes it an indispensable reagent for constructing complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of various heterocyclic compounds, active pharmaceutical ingredients (APIs), and prodrugs.
  • Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific brominated malonate structures.
  • Organic Synthesis Reagent: Employed in classic reactions like the Reformatsky reaction and other carbon-carbon bond formations to introduce functionalized malonate units.
  • Specialty Chemical Manufacturing: Serves as a precursor for dyes, pigments, and advanced polymer materials.
  • Research & Development: A valuable tool in medicinal chemistry and process chemistry for exploring new synthetic routes and molecular entities.
  • Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value fine chemicals and flavors/fragrances intermediates.

Basic Information

Product Name Diethyl Bromomalonate
CAS No. 685-87-0
Molecular Formula C7H11BrO4
Molecular Weight 239.07 g/mol
Synonyms Bromomalonic Acid Diethyl Ester; Diethyl 2-Bromomalonate; Ethyl Bromomalonate; 2-Bromomalonic Acid Diethyl Ester; Diethyl Bromopropanedioate; Bromodiethyl Malonate; Malonic Acid, Bromo-, Diethyl Ester; Propanedioic Acid, 2-Bromo-, 1,3-Diethyl Ester
EINECS 211-692-8

Quality Control

Our Diethyl Bromomalonate is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) for each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and reproducible synthetic results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Refractive Index 1.455 - 1.465
Density 1.45 - 1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.