Description

2-(Trifluoromethyl)Pyrimidin-4-Amine is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers for custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the CF3 group for improved efficacy.
• Material Science Research: Serves as a precursor for functionalized heterocycles used in organic electronics and specialty polymers.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry and biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(Trifluoromethyl)Pyrimidin-4-Amine
CAS No.	672-42-4
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	4-Amino-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)-4-pyrimidinamine; 4-Pyrimidinamine, 2-(trifluoromethyl)-; 2-Trifluoromethylpyrimidin-4-ylamine; α,α,α-Trifluoro-4-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.