Description

1-Aziridinecarboxylic Acid Isopropyl Ester is a versatile and highly reactive aziridine derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in its strained three-membered aziridine ring, which readily undergoes ring-opening reactions, making it an excellent precursor for introducing functionalized amine moieties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries, where it is used to develop active ingredients, specialty monomers, and cross-linking agents.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex molecules with nitrogen-containing heterocycles, useful in developing novel active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the production of herbicides, fungicides, and insecticides that require specific amine functionalities for bioactivity.
• Polymer & Resin Modification: Acts as a reactive monomer or cross-linking agent to introduce tertiary amine groups into polymer backbones, enhancing properties like adhesion, curing, and chemical resistance.
• Bioconjugation & Linker Chemistry: Utilized in bioconjugation strategies to attach labels, drugs, or probes to biomolecules via its reactive aziridine group.
• Organic Synthesis Reagent: Serves as a versatile reagent for nucleophilic ring-opening reactions, enabling the synthesis of β-amino esters and other functionalized compounds.
• Surface Coating Additive: Incorporated into coatings and adhesives to improve cross-linking density and final material performance.

Basic Information

Product Name	1-Aziridinecarboxylic Acid Isopropyl Ester
CAS No.	671-52-3
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	Isopropyl Aziridine-1-carboxylate; 1-Aziridinecarboxylic Acid, 1-Methylethyl Ester; Aziridine-1-carboxylic Acid Isopropyl Ester; Isopropyl 1-Aziridinecarboxylate; 1-Isopropoxycarbonylaziridine; NSC 163044; Ethylenimine-1-carboxylic Acid Isopropyl Ester
EINECS	211-577-4

Quality Control

Our 1-Aziridinecarboxylic Acid Isopropyl Ester is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.00 - 1.05
Refractive Index (n20D)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.