Description

2-Azaspiro[3.3]heptane is a versatile, nitrogen-containing spirocyclic building block of significant interest in modern organic synthesis. Its unique bridged bicyclic structure provides a rigid, three-dimensional scaffold that is highly valuable for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Scaffold: Used as a privileged structure in fragment-based drug design and combinatorial chemistry libraries to explore new chemical space and improve drug-like properties.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and molecular recognition applications.
• Agrochemical Research: Serves as a building block for novel crop protection agents and pesticides, leveraging its spirocyclic framework.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds and probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Azaspiro[3.3]heptane
CAS No.	665-04-3
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	2-Azaspiro[3.3]heptane; 1-Azabicyclo[3.1.1]heptane; 2-Azabicyclo[3.1.1]heptane; 1-Azaspiro[3.3]heptane; NSC 102816; Spiro[cyclopropane-1,2'-azetidine]; 2-Azaspiro(3.3)heptane
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.3]heptane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, GC analysis, NMR, and mass spectrometry for full structural confirmation and impurity profiling. Certificates of Analysis (COA) are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.