Description

Spiro[Bicyclo[3.1.1]Heptane-3,2-[1,3]Dioxolane] (9Ci) is a specialized spirocyclic organic compound featuring a fused bicyclo[3.1.1]heptane and dioxolane structure. This unique molecular architecture makes it a valuable advanced intermediate or building block for complex organic synthesis, particularly in the development of novel chemical entities. It is primarily sought by pharmaceutical R&D and fine chemical sectors for creating compounds with specific steric and electronic properties.

Application

• Pharmaceutical Intermediate: Serves as a key chiral or constrained scaffold in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, or insecticides where the spirocyclic structure can enhance biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for synthesizing polymers and advanced materials with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Fragrance and Flavor Chemistry: Potential use in synthesizing novel odorants or flavoring agents that require complex, bicyclic frameworks.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Item	Detail
Product Name	Spiro[Bicyclo[3.1.1]Heptane-3,2-[1,3]Dioxolane] (9Ci)
CAS No.	649-92-3
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	Spiro(bicyclo[3.1.1]heptane-3,2'-[1,3]dioxolane); 2,4-Dioxaspiro[bicyclo[3.1.1]heptane-3,2'-[1,3]dioxolane]; 3,9-Dioxa-1,5-dispiro[3.3]heptane (incorrect but sometimes used); Bicyclo[3.1.1]heptane-3,2'-[1,3]dioxolane, spiro-; 649-92-3; Spirocyclic dioxolane derivative of bicyclo[3.1.1]heptane
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[3.1.1]Heptane-3,2-[1,3]Dioxolane] (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.