Description

2-Hydroxychalcone is a versatile organic compound belonging to the chalcone family, characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a crucial synthetic intermediate and a privileged scaffold in medicinal chemistry for developing novel bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing flavonoids and other heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Core scaffold for developing novel drug candidates targeting inflammation, cancer, and microbial infections.
• Organic Synthesis: Used in various condensation and cyclization reactions to create complex molecular architectures.
• Agrochemical Development: Intermediate in the synthesis of new plant protection agents and growth regulators.
• Material Science: Investigated as a precursor for organic semiconductors and photonic materials due to its conjugated system.
• Biochemical Tool: Used in studies to understand enzyme inhibition and cellular signaling pathways.

Basic Information

Product Name	2-Hydroxychalcone
CAS No.	644-78-0
Molecular Formula	C15H12O2
Molecular Weight	224.26 g/mol
Synonyms	2'-Hydroxychalcone; (E)-1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one; 2-Hydroxybenzalacetophenone; o-Hydroxychalcone; 1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one; NSC 407259; Benzalacetophenone, 2'-hydroxy-
EINECS	211-433-8

Quality Control

Our 2-Hydroxychalcone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.