Description

Hexa-o-Acetyl-D-Mannitol is a fully acetylated derivative of D-mannitol, a sugar alcohol. This compound serves as a crucial advanced intermediate and building block in organic synthesis, particularly for the production of complex carbohydrates and chiral molecules. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where high-purity chiral intermediates are required.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Chiral Synthesis: Utilized as a chiral pool reagent or auxiliary in asymmetric synthesis to introduce stereochemistry.
• Glycochemistry Research: Serves as a protected mannitol derivative for the study and synthesis of oligosaccharides, glycoconjugates, and glycomimetics.
• Agrochemical Production: Intermediate in the manufacture of certain herbicides and plant growth regulators with specific stereochemical requirements.
• Polymer Science: Potential monomer or cross-linking agent for creating specialty polyesters or polyurethanes with unique properties.
• Cosmetic & Personal Care: Used in the synthesis of specialty esters that may function as emollients or texture enhancers.

Basic Information

Product Name	Hexa-o-Acetyl-D-Mannitol
CAS No.	642-00-2
Molecular Formula	C18H26O12
Molecular Weight	434.39 g/mol
Synonyms	D-Mannitol Hexaacetate; 1,2,3,4,5,6-Hexa-O-acetyl-D-mannitol; D-Mannitol, hexaacetate; Mannitol hexaacetate; Hexaacetylmannitol; Acetylated D-Mannitol; NSC 401005; Hexa-O-acetyl-1,2,3,4,5,6-mannitol
EINECS	211-389-8

Quality Control

Our Hexa-o-Acetyl-D-Mannitol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for use as a fine chemical intermediate. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Specific Rotation [α]20/D	+23.0° to +25.0° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.