Description

Isoamylisocyanide is a versatile organic building block and ligand, widely recognized for its utility in organometallic chemistry and heterocyclic synthesis. Its primary value lies in its role as a crucial isocyanide component for the Passerini and Ugi multicomponent reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create novel compounds and advanced materials.

Application

• Pharmaceutical Intermediates: A key reagent in multicomponent reactions (MCRs) like the Ugi and Passerini reactions for rapid library synthesis of drug-like molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides through isocyanide-based coupling chemistry.
• Coordination Chemistry: Serves as a ligand for transition metals, forming complexes used in catalysis and material science.
• Heterocyclic Chemistry: Integral to the synthesis of various nitrogen-containing heterocycles, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Employed in the synthesis of functional polymers and smart materials with tailored properties.
• Chemical Biology: Utilized in bio-conjugation and probe development for studying biological systems.

Basic Information

Product Name	Isoamylisocyanide
CAS No.	638-27-7
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	3-Methylbutyl isocyanide; Isopentyl isocyanide; Isoamyl isonitrile; 1-Isocyano-3-methylbutane; (3-Methylbutyl)isocyanide; Isovaleryl isocyanide (common misnomer); Isopentylisonitrile
EINECS	211-347-8

Quality Control

Our Isoamylisocyanide is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and fine chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.