Description

Clofibrate is an organic compound belonging to the class of fibrates, primarily recognized for its role as a lipid-modifying agent. This compound is a key pharmaceutical intermediate and research chemical, valued for its specific biological activity in metabolic studies. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors developing or studying hypolipidemic agents.

Application

• Pharmaceutical Intermediate: Primary use as a key starting material (KSM) or active pharmaceutical ingredient (API) in the synthesis of lipid-regulating medications.
• Biomedical Research: Utilized in preclinical and in vitro studies to investigate mechanisms of action related to peroxisome proliferator-activated receptor alpha (PPAR-α) activation and triglyceride metabolism.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Metabolic Disorder Studies: Applied in research models for dyslipidemia, atherosclerosis, and other cardiovascular-related metabolic conditions.
• Chemical Synthesis: Used as a building block or precursor in organic synthesis for creating novel derivatives with potential therapeutic value.

Basic Information

Item	Details
Product Name	Clofibrate
CAS No.	637-07-0
Molecular Formula	C12H15ClO3
Molecular Weight	242.70 g/mol
Synonyms	Ethyl 2-(4-Chlorophenoxy)-2-methylpropionate; Atromid-S; Clofibrate Ethyl Ester; 2-(p-Chlorophenoxy)-2-methylpropionic Acid Ethyl Ester; Ethyl Chlorophenoxyisobutyrate; CPIB; ICI 28257; Liprinal; Regelan
EINECS	211-292-5

Quality Control

Our Clofibrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.