Description

(+)-Epinephrine Bitartrate CAS NO 636-89-5 is the L-isomer salt form of the essential hormone and neurotransmitter epinephrine (adrenaline). This high-purity chiral compound is critical for ensuring precise pharmacological activity in advanced therapeutic formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing or producing emergency medications, cardiac stimulants, and specialized diagnostic agents.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable formulations for emergency treatment of anaphylaxis, cardiac arrest, and severe asthma attacks.
• Cardiovascular Research: Standard reference compound in studies of adrenergic receptors, vasoconstriction, and cardiac output.
• Ophthalmic Solutions: Used in glaucoma treatment and as a mydriatic (pupil dilator) in surgical procedures.
• Local Anesthetic Adjuvant: Added to local anesthetics like lidocaine to prolong their duration of action by causing vasoconstriction.
• Diagnostic Agent: Employed in diagnostic tests for autonomic nervous system function and certain metabolic disorders.
• Veterinary Medicine: Essential for emergency kits in veterinary practice for treating anaphylaxis and cardiac support in animals.

Basic Information

Product Name	(+)-Epinephrine Bitartrate
CAS No.	636-89-5
Molecular Formula	C9H13NO3 • C4H6O6
Molecular Weight	333.29 g/mol
Synonyms	L-Epinephrine Bitartrate; (-)-3,4-Dihydroxy-α-[(methylamino)methyl]benzyl Alcohol Tartrate (1:1); Adrenaline Bitartrate; Epinephrine Hydrogen Tartrate; Levorenin Bitartrate; Adrenaline Acid Tartrate; 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Suprarenin Bitartrate
EINECS	211-264-5

Quality Control

Our (+)-Epinephrine Bitartrate is manufactured under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container tightly sealed in a dry, cool, and well-ventilated place. Avoid exposure to excessive heat and moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-50.0° to -53.5° (c = 2 in water)
pH (1% Solution)	3.0 - 4.0
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.