Description

Ethyl 2-Cyanoacetoacetate is a versatile and high-purity organic ester, serving as a critical building block in advanced chemical synthesis. Its value lies in its bifunctional cyano and keto ester groups, which enable its use in constructing complex heterocyclic and pharmaceutical intermediates. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality raw materials for their production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyridine, pyrimidine, and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacturing of advanced pesticides, herbicides, and fungicides, where its reactive sites allow for the introduction of specific functional groups.
• Fine Chemical Production: Employed as a versatile synthon for creating complex molecules used in dyes, pigments, and specialty polymers.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and developing novel compounds.
• Chemical Synthesis Building Block: Utilized in condensation and cyclization reactions, such as the Gewald reaction, to produce 2-aminothiophenes and related derivatives.

Basic Information

Product Name	Ethyl 2-Cyanoacetoacetate
CAS No.	634-55-9
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	Ethyl Cyanoacetoacetate; Ethyl 2-Cyano-3-oxobutanoate; 2-Cyanoacetoacetic Acid Ethyl Ester; Acetoacetic Acid, Cyano-, Ethyl Ester; Cyanoacetic Acid Ethyl Ester Ketone; Ethyl α-Cyanoacetoacetate; NSC 401787
EINECS	211-209-0

Quality Control

Our Ethyl 2-Cyanoacetoacetate is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. We adhere to relevant industry standards, and our quality control protocols include comprehensive analytical testing. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.438 - 1.442
Density (20°C)	1.10 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.