Description

3-Fluoromevalonate (CAS NO 631-43-6) is a fluorinated derivative of mevalonic acid, a key intermediate in the biosynthesis of isoprenoids and sterols. This compound is valued for its role as a biochemical tool and a versatile building block in advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing novel compounds and studying enzymatic pathways.

Application

• Biochemical Research: Used as a metabolic probe to study the mevalonate pathway and the effects of fluorination on enzyme activity, particularly in sterol and isoprenoid biosynthesis.
• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of fluorinated drug candidates, including potential enzyme inhibitors and metabolic modulators.
• Agrochemical Development: Employed in the synthesis of novel fluorinated active ingredients for crop protection products, leveraging fluorine's ability to enhance stability and bioavailability.
• Organic Synthesis Building Block: Acts as a chiral precursor for the synthesis of complex, fluorinated natural product analogs and specialty chemicals.
• Enzyme Inhibition Studies: Utilized to investigate and characterize the inhibition of key enzymes like HMG-CoA reductase in metabolic research.

Basic Information

Product Name	3-Fluoromevalonate
CAS No.	631-43-6
Molecular Formula	C6H11FO4
Molecular Weight	166.15 g/mol
Synonyms	3-Fluoromevalonic Acid; (R)-3-Fluoromevalonate; 3-Fluoro-3,5-dihydroxy-3-methylpentanoic Acid; 3-Fluoro-3-methyl-3,5-dihydroxypentanoic Acid; Mevalonic Acid, 3-Fluoro-; 3-Fluoro-3-methylpentanedioic Acid 5-Hydroxy-3-methyl ester; 3-Fluoromevalonic Acid Lactone (for lactone form)
EINECS	Contact for details

Quality Control

Our 3-Fluoromevalonate is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity and spectroscopic identification (NMR, IR). Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.