Description

4-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive chlorine atom, which enables efficient cross-coupling reactions and functional group transformations to create complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), including potential antiviral and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used to construct pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and conductive polymers.
• Chemical Research & Development: A fundamental reagent for exploring novel heterocyclic compounds and reaction methodologies in academic and industrial labs.
• Custom Synthesis: Building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	4-Chloropyridine
CAS No.	626-61-9
Molecular Formula	C5H4ClN
Molecular Weight	113.54 g/mol
Synonyms	γ-Chloropyridine; 4-Chloro-pyridine; p-Chloropyridine; NSC 9376; Pyridine, 4-chloro-; 4-Pyridyl chloride
EINECS	210-959-0

Quality Control

Our 4-Chloropyridine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (GC/HPLC)	≤2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.