Description

3,5-Dibromopyridine CAS NO 625-92-3 is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of two bromine atoms on the pyridine ring, which enables selective functionalization for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their synthetic workflows.

Application

3,5-Dibromopyridine is a versatile intermediate prized for its reactivity in cross-coupling reactions and nucleophilic substitutions. Its primary applications include:

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing functionalized pyridine cores, such as kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides where the dibromopyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized nitrogen-containing ligands used in homogeneous catalysis.
• Material Science Research: Employed in the development of organic electronic materials, including charge-transport layers and light-emitting compounds.
• Chemical Research & Development: A fundamental reagent for method development in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and functional polymers.

Basic Information

Product Name	3,5-Dibromopyridine
CAS No.	625-92-3
Molecular Formula	C5H3Br2N
Molecular Weight	236.89 g/mol
Synonyms	3,5-Dibromopyridine; Pyridine, 3,5-dibromo-; 3,5-DBP; NSC 40156; AI3-52202; CCRIS 6055; HSDB 8247; 3,5-Dibromopyridin; 3,5-Dibromopyridina; 3,5-二溴吡啶
EINECS	210-915-4

Quality Control

Our 3,5-Dibromopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency meet the stringent requirements of our global B2B clients. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	112 - 116 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.