Description

Azidomethane is a highly reactive organic azide compound, valued for its role as a versatile building block in synthetic organic chemistry. Its primary commercial significance lies in its ability to act as a potent methyl azide transfer agent, facilitating the introduction of the azido functional group into complex molecular frameworks. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of heterocycles, energetic materials, and click chemistry substrates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of triazole and tetrazole-based active pharmaceutical ingredients (APIs) via click chemistry and cycloaddition reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate nitrogen-rich heterocyclic structures.
• Energetic Materials Research: Serves as a fundamental component in the research and development of high-energy-density materials (HEDMs) and propellants.
• Polymer Modification: Employed to functionalize polymers and materials surfaces through azide-alkyne Huisgen cycloaddition, imparting new properties.
• Chemical Biology & Proteomics: Utilized as a bioorthogonal reagent for labeling and studying biomolecules in living systems.
• Organic Synthesis Reagent: Acts as a source of the N3 group in various organic transformations, including nucleophilic substitutions and 1,3-dipolar cycloadditions.

Basic Information

Product Name	Azidomethane
CAS No.	624-90-8
Molecular Formula	CH3N3
Molecular Weight	57.05 g/mol
Synonyms	Methyl azide; Azidomethane; Monomethyl azide; Methane, azido-; NSC 8441; Methylazide; Azidomethan (German)
EINECS	210-866-3

Quality Control

Our Azidomethane is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. We adhere to cGMP principles where applicable, and all material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. For specific regulatory or pharmacopeial requirements, please contact our technical support team.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and potentially shock-sensitive nature, store in a cool (recommended 2-8°C), well-ventilated, dedicated area away from heat, ignition sources, and incompatible materials. Containers must be kept tightly sealed under an inert atmosphere to minimize decomposition and pressure build-up. Follow all relevant local and international regulations for the storage of reactive azides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.