Description

Ethyl Cyanoformate is a versatile and highly reactive organic ester, widely recognized for its role as a key building block in chemical synthesis. Its primary value lies in its bifunctional nature, containing both an ester and a highly electrophilic cyano group, making it an essential reagent for introducing the cyanoformate moiety into target molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of heterocyclic compounds, carbamates, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where it acts as a precursor for various functional groups.
• Peptide Chemistry: Serves as a coupling agent or protecting group reagent in peptide synthesis and modification.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for creating specialty polymers with specific functional properties.
• Organic Synthesis Reagent: Utilized in various name reactions and transformations, such as cyanoformylation, to construct complex molecular architectures.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in exploratory synthesis and route scouting.

Basic Information

Product Name	Ethyl Cyanoformate
CAS No.	623-49-4
Molecular Formula	C4H5NO2
Molecular Weight	99.09 g/mol
Synonyms	Ethyl Cyanoformate; Ethyl Carbonocyanidate; Cyanoformic Acid Ethyl Ester; Ethyl Cyanoformiate; Ethyl Ester of Cyanoformic Acid; NSC 8826; Ethoxycarbonyl Cyanide; Carbonocyanidic Acid, Ethyl Ester
EINECS	210-793-8

Quality Control

Our Ethyl Cyanoformate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to confirm identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards and can support development projects requiring specific analytical methodologies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile and reactive nature, it should be kept under an inert atmosphere (e.g., nitrogen) to maintain stability and prevent moisture ingress or decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density	1.00 - 1.10 g/mL @ 20°C
Refractive Index	1.390 - 1.410 @ 20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.