Description

Ethyl Iodoacetate is a versatile alkylating agent and a key building block in organic synthesis. This compound is valued for its reactivity, particularly in introducing the iodoacetate moiety into target molecules, enabling the synthesis of more complex structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in the construction of heterocyclic compounds and as a precursor for targeted drug molecules.
• Agrochemical Synthesis: Serves as a key intermediate in the production of herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Protein Modification: Acts as an alkylating agent for modifying cysteine residues in proteins and peptides for biochemical research and biopharmaceutical development.
• Organic Synthesis Reagent: Employed in various carbon-carbon bond forming reactions, esterifications, and as a source of the -CH2COOEt synthon.
• Material Science: Utilized in the surface modification of polymers and the synthesis of functional monomers for advanced materials.
• Research & Development: A critical tool in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	Ethyl Iodoacetate
CAS No.	623-48-3
Molecular Formula	C4H7IO2
Molecular Weight	214.00 g/mol
Synonyms	Iodoacetic Acid Ethyl Ester; Ethyl 2-Iodoacetate; 2-Iodoacetic Acid Ethyl Ester; Acetic Acid, Iodo-, Ethyl Ester; Ethyl Monoiodoacetate; Monoiodoacetic Acid Ethyl Ester; NSC 9248; Ethyl α-Iodoacetate
EINECS	210-795-0

Quality Control

Our Ethyl Iodoacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (by GC/HPLC), identity confirmation (IR), and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Refractive Index (n20/D)	1.506 - 1.510
Density (g/mL, 25°C)	1.80 - 1.85
Related Substances (HPLC)	Report and comply with agreed limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.