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p-Tolyl Isocyanate CAS NO 622-58-2
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CAS No.:622-58-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
p-Tolyl Isocyanate is a versatile aromatic isocyanate monomer essential for synthesizing high-performance polymers and specialty chemicals. Its reactivity with compounds containing active hydrogen atoms makes it a critical building block for creating materials with tailored properties. This compound is particularly valuable for manufacturers in the agrochemical, pharmaceutical, and advanced materials sectors seeking to develop custom polyurethanes, ureas, and carbamates.
Application
- Agrochemical Intermediates: Key precursor in the synthesis of phenylurea herbicides and other crop protection agents.
- Pharmaceutical Synthesis: Used as a reagent for introducing the tolyl carbamoyl moiety in active pharmaceutical ingredients (APIs).
- Polyurethane & Coatings: Serves as a cross-linking agent and hard segment component in specialty polyurethane coatings, adhesives, and elastomers requiring specific chemical resistance.
- Chemical Intermediate: Fundamental building block for producing carbamates, ureas, and other isocyanate-derived fine chemicals.
- Polymer Modification: Employed to functionalize polymers and resins, enhancing their adhesion, durability, or compatibility.
- Research & Development: Utilized in laboratories for method development and the creation of novel compounds in material science.
Basic Information
| Product Name | p-Tolyl Isocyanate |
| CAS No. | 622-58-2 |
| Molecular Formula | C8H7NO |
| Molecular Weight | 133.15 g/mol |
| Synonyms | 4-Methylphenyl isocyanate; 4-Tolyl isocyanate; p-Methylphenyl isocyanate; 1-Isocyanato-4-methylbenzene; Isocyanic acid, 4-methylphenyl ester; 4-Toluenyl isocyanate; NSC 9405; PTI |
| EINECS | 210-743-7 |
Quality Control
Our p-Tolyl Isocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical testing, including assay by GC/HPLC and impurity profiling, to meet the stringent requirements of our industrial and research partners. A Certificate of Analysis (COA) detailing all specifications is available for every shipment upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under a dry inert atmosphere (e.g., nitrogen) to prevent hydrolysis and polymerization. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow liquid |
| Identification (IR) | Conforms |
| Assay (GC/HPLC) | ≥ 98.0% |
| Color (APHA) | ≤ 50 |
| Water Content (KF) | ≤ 0.1% |
| p-Toluidine (HPLC) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





