Description

Hyoscyamine Sulfate is a high-purity pharmaceutical-grade alkaloid salt derived from plants of the Solanaceae family. This compound serves as a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of anticholinergic medications. It is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring a reliable, high-quality source for producing treatments for gastrointestinal and genitourinary spasms. Our product, Hyoscyamine Sulfate CAS NO 620-61-1, is supplied under strict quality control to ensure batch-to-batch consistency and regulatory compliance.

Application

• Pharmaceutical API: Primary active ingredient in prescription medications for treating gastrointestinal disorders, such as irritable bowel syndrome (IBS) and peptic ulcers.
• Antispasmodic Formulations: Used in the production of drugs that relieve smooth muscle spasms in the urinary tract and biliary system.
• Pre-Anesthetic Medication: Component in formulations to reduce salivary and bronchial secretions before surgery.
• Ophthalmic Solutions: Intermediate in the manufacture of cycloplegic and mydriatic eye drops used for pupil dilation.
• Research & Development: Reference standard and building block in pharmacological research for studying muscarinic acetylcholine receptors.
• Veterinary Medicine: Used in veterinary pharmaceuticals for similar antispasmodic and antisecretory applications in animals.

Basic Information

Product Name	Hyoscyamine Sulfate
CAS No.	620-61-1
Molecular Formula	C34H48N2O10S
Molecular Weight	676.82 g/mol
Synonyms	Hyoscyamine Sulphate; (3(S)-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (S)-tropate sulfate (2:1); Atropine Impurity C; Daturine Sulfate; Duboisine Sulfate; L-Hyoscyamine Sulfate; Tropine Tropate Sulfate
EINECS	210-645-9

Quality Control

Our Hyoscyamine Sulfate is manufactured and tested to meet stringent pharmacopeial standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines, and our quality system supports compliance with major international standards, including USP and EP monographs where applicable. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Specific Rotation	-24° to -28° (c = 5 in H2O)
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.