Description

4-Fluoro-3-Iodobenzoic Acid Ethyl Ester is a versatile fluorinated and iodinated aromatic ester, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of halogen atoms, which enable selective cross-coupling reactions and facilitate the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Fluorine Chemistry Research: The fluorine substituent makes it valuable for studying structure-activity relationships (SAR) and metabolic stability in compound libraries.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Fluoro-3-Iodobenzoic Acid Ethyl Ester
CAS No.	618-93-9
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Ethyl 4-Fluoro-3-iodobenzoate; Benzoic acid, 4-fluoro-3-iodo-, ethyl ester; 3-Iodo-4-fluorobenzoic acid ethyl ester; 4-Fluoro-3-iodobenzoic acid ethyl ester; Ethyl 3-iodo-4-fluorobenzoate; 618-93-9; 4-Fluoro-3-iodo-benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Iodobenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.