Description

trans-Chalcone CAS NO 614-47-1 is a versatile organic compound belonging to the chalcone class, characterized by its α,β-unsaturated ketone structure. This chemical serves as a crucial synthetic intermediate and a privileged scaffold in medicinal chemistry for developing novel bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents, flavors, or functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing flavonoids, benzodiazepines, and other heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold to develop and screen new drug candidates for anti-inflammatory, anticancer, antimicrobial, and antioxidant properties.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and plant growth regulators.
• Flavor and Fragrance Industry: Utilized in the synthesis of certain aroma compounds and flavoring agents.
• Organic Synthesis & Material Science: Acts as a Michael acceptor in organic reactions and a monomer for creating polymers with specific optical or electronic properties.
• Biochemical Research: Employed as a standard or inhibitor in enzymatic studies, particularly those involving tyrosine kinases or other cellular pathways.

Basic Information

Product Name	trans-Chalcone
CAS No.	614-47-1
Molecular Formula	C15H12O
Molecular Weight	208.26 g/mol
Synonyms	(E)-Chalcone; Benzylideneacetophenone; (E)-1,3-Diphenyl-2-propen-1-one; (E)-1,3-Diphenylprop-2-en-1-one; 3-Phenyl-1-phenyl-2-propen-1-one; trans-1,3-Diphenyl-2-propen-1-one; trans-Benzylideneacetophenone; α-Phenylcinnamaldehyde (deprecated)
EINECS	210-400-1

Quality Control

Our trans-Chalcone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	55 - 58 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.