Description

2-Hydroxynicotinic Acid is a versatile heterocyclic carboxylic acid derivative of pyridine, serving as a key organic intermediate and building block in advanced synthesis. Its bifunctional structure, containing both a hydroxyl and a carboxylic acid group on the pyridine ring, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific pyridine-based structures.
• Ligand and Chelating Agent: Serves as a precursor for creating complexing agents and ligands in coordination chemistry and catalysis due to its donor atoms.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional organic materials.
• Biochemical Research: Acts as a synthetic analog or precursor in the study of nicotinic acid derivatives and related metabolic pathways.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of specialty chemicals for various industrial and research applications.

Basic Information

Product Name	2-Hydroxynicotinic Acid
CAS No.	609-71-2
Molecular Formula	C6H5NO3
Molecular Weight	139.11 g/mol
Synonyms	2-Hydroxypyridine-3-carboxylic Acid; 3-Carboxy-2-hydroxypyridine; 2-Pyridinol-3-carboxylic Acid; 2-Hydroxy-3-pyridinecarboxylic Acid; 3-Pyridinecarboxylic Acid, 2-hydroxy-; 2-Hydroxynicotinate; 6-Hydroxynicotinic Acid (tautomer); 2-Oxopyridine-3-carboxylic Acid
EINECS	210-200-9

Quality Control

Our 2-Hydroxynicotinic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation via FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	260°C - 265°C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.