Description

Diethyl Ketomalonate is a versatile organic building block and a key intermediate in fine chemical synthesis. Its high reactivity, particularly as a precursor to heterocyclic compounds, makes it invaluable for creating complex molecular architectures. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various heterocyclic compounds, including pyrazoles, isoxazoles, and other nitrogen-containing rings found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its ketone and ester functionalities.
• Fine Chemical Manufacturing: Serves as a building block for dyes, pigments, and complex organic molecules requiring specific ketomalonate frameworks.
• Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new synthetic pathways.
• Coordination Chemistry: Acts as a ligand or precursor for ligands in metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	Diethyl Ketomalonate
CAS No.	609-09-6
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	Diethyl 2-oxomalonate; Diethyl mesoxalate; Ketomalonic acid diethyl ester; Ethyl ketomalonate; Oxomalonic acid diethyl ester; Diethyl oxomalonate; Mesoxalic acid diethyl ester; Ethyl mesoxalate
EINECS	210-185-9

Quality Control

Our Diethyl Ketomalonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. The container must be kept tightly sealed due to sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.