Description

Butanedioic Acid, 2,3-Dihydroxy-, Dimethyl Ester, (2R,3R)-Rel- is a high-purity chiral building block and intermediate of significant commercial interest. This compound is valued for its defined stereochemistry, which is critical for synthesizing optically active molecules in advanced chemical manufacturing. It serves as a key precursor for pharmaceutical actives, agrochemicals, and specialty fine chemicals where precise molecular configuration dictates biological activity and material properties.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and cardiovascular drug development.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for chiral ligands, catalysts, and complex organic molecules used in asymmetric synthesis.
• Flavor and Fragrance Industry: Potential intermediate for creating specific stereoisomers of flavor compounds and aroma chemicals.
• Academic and R&D: Employed in chemical research for studying stereoselective reactions and developing new synthetic methodologies.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer for producing polymers with specific tacticity and properties.

Basic Information

Product Name	Butanedioic Acid, 2,3-Dihydroxy-, Dimethyl Ester, (2R,3R)-Rel-
CAS No.	608-69-5
Molecular Formula	C6H10O6
Molecular Weight	178.14 g/mol
Synonyms	Dimethyl (2R,3R)-2,3-Dihydroxysuccinate; (2R,3R)-Dimethyl Tartrate; D-(-)-Dimethyl Tartrate; Rel-(2R,3R)-2,3-Dihydroxybutanedioic Acid Dimethyl Ester; Dimethyl L-Threarate; (R,R)-Dimethyl Tartrate; L-(-)-Dimethyl Tartrate; Dimethyl (R,R)-Tartrate
EINECS	210-163-9

Quality Control

Our Butanedioic Acid, 2,3-Dihydroxy-, Dimethyl Ester, (2R,3R)-Rel- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting specifications for chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]20/D	-15.0° to -18.0° (c=1 in H2O)
Melting Point	88°C - 92°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.