Description

Biotin Methyl Ester CAS NO 608-16-2 is a chemically modified derivative of biotin (Vitamin B7), where the carboxylic acid group is esterified with methanol. This modification enhances its lipophilicity, making it a crucial intermediate in the synthesis of biotinylated compounds for research and industrial applications. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and life science research sectors for developing targeted biochemical probes and active pharmaceutical ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel biotin-conjugated drugs and targeted therapeutic agents.
• Biochemical Research: Used to prepare biotinylated probes, tags, and substrates for studying protein interactions, enzyme kinetics, and cellular localization.
• Diagnostic Reagent Production: Serves as a precursor in manufacturing components for immunoassays, biosensors, and other diagnostic kits that utilize the strong biotin-streptavidin binding system.
• Nutraceutical Formulation: Employed in the development of specialized, high-bioavailability vitamin supplements and fortified products.
• Cosmetic Ingredient Synthesis: Used in the production of advanced cosmetic actives that leverage biotin's role in skin and hair health.
• Chemical Reference Standard: Provides a certified standard material for quality control and analytical method development in laboratories.

Basic Information

Product Name	Biotin Methyl Ester
CAS No.	608-16-2
Molecular Formula	C11H18N2O3S
Molecular Weight	258.34 g/mol
Synonyms	Biotin methyl ester; D-Biotin methyl ester; (+)-Biotin methyl ester; Vitamin B7 methyl ester; Vitamin H methyl ester; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid methyl ester; Methyl D-biotinate
EINECS	210-159-0

Quality Control

Our Biotin Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +89° to +93° (c=1 in 0.1N NaOH)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.