Description

Norethynodrel CAS NO 68-23-5 is a synthetic progestin and a key pharmaceutical intermediate. It is historically significant as a primary component in the first commercially available oral contraceptive. This compound is essential for manufacturers in the pharmaceutical and life sciences sectors requiring high-purity steroid intermediates for research and production.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the synthesis of specific steroid-based active pharmaceutical ingredients (APIs).
• Hormone Research: Used in biochemical and pharmacological research to study progestogenic activity and hormone receptor interactions.
• Reference Standard: Serves as a certified reference standard (CRS) or working standard in analytical laboratories for quality control and method validation.
• Academic & Contract Research: Utilized in university and CRO settings for synthetic chemistry projects and the development of novel therapeutic agents.

Basic Information

Product Name	Norethynodrel
CAS No.	68-23-5
Molecular Formula	C₂₀H₂₆O₂
Molecular Weight	298.42 g/mol
Synonyms	17α-Ethynyl-17β-hydroxy-5(10)-estren-3-one; 17-Hydroxy-19-nor-17α-pregn-5(10)-en-20-yn-3-one; 19-Nor-17α-pregn-5(10)-en-20-yne-3,17-diol; Enovid (component); SC-4642; Norinyl (component); Conovid (component)
EINECS	200-682-4

Quality Control

Our Norethynodrel is produced and tested under strict quality management systems. We offer material suitable for use as a pharmaceutical intermediate, with specifications tailored to customer requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each batch to ensure traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.