Description

Propiomazine Hydrochloride is a phenothiazine derivative with significant sedative and antihistaminic properties. This compound is a critical active pharmaceutical ingredient (API) valued for its potent central nervous system activity. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of sedative and pre-anesthetic medications.

Application

• Pharmaceutical API: Primary use as an active ingredient in sedative and hypnotic drug formulations.
• Pre-anesthetic Medication: Used in medical settings to induce sedation prior to surgical procedures.
• Antihistaminic Agent: Employed in formulations targeting allergic reactions due to its histamine H1-receptor antagonism.
• Veterinary Medicine: Application in veterinary pharmaceuticals for sedation and tranquilization.
• Chemical Reference Standard: Serves as a high-purity standard in analytical laboratories for quality control and method development.
• Research & Development: Used in pharmacological and neurochemical research to study phenothiazine derivatives and their effects.

Basic Information

Product Name	Propiomazine Hydrochloride
CAS No.	64-89-1
Molecular Formula	C20H24N2OS • HCl
Molecular Weight	376.94 g/mol
Synonyms	Propiomazine HCl; Propavan; 10-[2-(Dimethylamino)propyl]phenothiazin-2-yl methyl ketone hydrochloride; 1-[10H-Phenothiazin-2-yl]-2-(dimethylamino)-1-propanone hydrochloride; Dorevan; Indorm; Largon; Propionylpromazine Hydrochloride
EINECS	200-600-3

Quality Control

Our Propiomazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.