Description

Estra-1,3,5(10),7-Tetraen-17-One, 3-Hydroxy-, Cyclic 1,2-Ethanediyl Acetal is a high-purity steroid derivative and a key protected intermediate in advanced organic synthesis. This compound is valued for its role in the development of complex pharmaceutical molecules, particularly in steroid and hormone research. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical and fine chemical industries for the synthesis of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and studying structure-activity relationships (SAR) in medicinal chemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Process Development: Used in scaling up and optimizing synthetic routes for commercial production within GMP environments.

Basic Information

Product Name	Estra-1,3,5(10),7-Tetraen-17-One, 3-Hydroxy-, Cyclic 1,2-Ethanediyl Acetal
CAS No.	64-22-2
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	Equilenin 3-Methyl Ether Cyclic Ethylene Acetal; 3-Methoxyestra-1,3,5(10),7-tetraen-17-one cyclic ethylene acetal; 3-Methoxy-17-oxoestra-1,3,5(10),7-tetraene cyclic 1,2-ethanediyl acetal; Equilenin 3-methyl ether cyclic ethylene ketal; NSC 35752; 17-Keto-3-methoxyestra-1,3,5(10),7-tetraene cyclic ethylene acetal
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10),7-Tetraen-17-One, 3-Hydroxy-, Cyclic 1,2-Ethanediyl Acetal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.