Description

Benzenemethanol, α-[(1R)-1-Aminoethyl]-3-Hydroxy-, (αs)- is a chiral amino alcohol derivative, serving as a critical building block in asymmetric synthesis. Its value lies in its ability to impart stereochemical control in the production of high-value pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations like hydrogenation and cross-coupling.
• Agrochemical Synthesis: Employed as a precursor in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	Benzenemethanol, α-[(1R)-1-Aminoethyl]-3-Hydroxy-, (αs)-
CAS No.	61-59-6
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(1R)-1-(3-Hydroxyphenyl)ethylamine; (R)-1-(3-Hydroxyphenyl)ethanamine; (R)-1-(3-Hydroxybenzyl)ethylamine; (R)-3-(1-Aminoethyl)phenol; (αR)-α-[(1-Aminoethyl)]-3-hydroxybenzenemethanol; (R)-HPEA; 3-Hydroxy-(R)-α-methylbenzylamine
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-[(1R)-1-Aminoethyl]-3-Hydroxy-, (αs)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.