Description

Methoxamine Hydrochloride CAS NO 61-16-5 is a selective α-1 adrenergic receptor agonist, widely recognized for its potent vasoconstrictive properties. This compound is of significant value in pharmaceutical research and development, particularly for studying cardiovascular physiology and as a reference standard. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis of active pharmaceutical ingredients (APIs) and preclinical pharmacological studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex adrenergic agents and related pharmaceutical compounds.
• Research Chemical: Used extensively in preclinical and biomedical research to study α-adrenergic receptor mechanisms, vascular tone, and blood pressure regulation.
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method validation in pharmaceutical laboratories.
• Vasopressor Agent: Employed in experimental models to induce vasoconstriction and study cardiovascular responses and drug interactions.
• Biochemical Tool: Utilized in receptor binding assays and functional studies to characterize agonist activity and selectivity.

Basic Information

Product Name	Methoxamine Hydrochloride
CAS No.	61-16-5
Molecular Formula	C11H17NO3 • HCl
Molecular Weight	247.72 g/mol
Synonyms	Methoxamine HCl; 2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol hydrochloride; α-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride; Vasoxyl; Vasoxine; Pressomin; Mexan; Methoxamedrine Hydrochloride
EINECS	200-500-4

Quality Control

Our Methoxamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) documenting purity, physical characteristics, and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.