Description

6-((Methylsulfonyl)Methyl)Nicotinic Acid Hydrochloride is a high-purity, functionalized nicotinic acid derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical, valued for its unique sulfonylmethyl side chain which facilitates further derivatization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Reagent: Acts as a versatile precursor for the introduction of the (methylsulfonyl)methyl functional group into more complex molecules.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and metabolic pathway studies.
• Material Science: Intermediate for the synthesis of specialty chemicals and functional materials requiring specific sulfone-containing motifs.

Basic Information

Product Name	6-((Methylsulfonyl)Methyl)Nicotinic Acid Hydrochloride
CAS No.	597562-49-7
Molecular Formula	C8H9NO4S • HCl
Molecular Weight	251.68 g/mol (Free base: 215.22 g/mol)
Synonyms	6-((Methylsulfonyl)methyl)pyridine-3-carboxylic acid hydrochloride; 3-Pyridinecarboxylic acid, 6-[(methylsulfonyl)methyl]-, hydrochloride (1:1); Nicotinic acid, 6-((methylsulfonyl)methyl)-, hydrochloride; 6-(Methylsulfonylmethyl)nicotinic acid HCl; 597562-49-7 (CAS); 6-MSM Nicotinic Acid HCl
EINECS	Contact for details

Quality Control

Our production of 6-((Methylsulfonyl)Methyl)Nicotinic Acid Hydrochloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if frequent access is required, and desiccate if necessary to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.