Description

1-Azacyclopropa[Cd]Pentalene-4A(1H)-Carboxylicacid,Hexahydro-2-Oxo-,Methylester,(2Ar,2Br,4As,4Bs)-(9Ci) is a complex, high-purity bicyclic lactam derivative with a defined stereochemistry, serving as a critical advanced intermediate in modern synthetic chemistry. This compound matters for its role in constructing intricate molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for use in asymmetric synthesis and as a key chiral building block.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting neurological and anti-infective pathways.
• Agrochemical Research: Used in the development of novel herbicides and pesticides with specific stereochemical requirements for enhanced activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: A valuable tool for methodological development in organic synthesis and stereochemistry studies.
• Material Science: Potential monomer or precursor for the synthesis of specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	1-Azacyclopropa[Cd]Pentalene-4A(1H)-Carboxylicacid,Hexahydro-2-Oxo-,Methylester,(2Ar,2Br,4As,4Bs)-(9Ci)
CAS No.	597540-62-0
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	(2aR,2bR,4aS,4bS)-Hexahydro-2-oxo-1H-1-azacyclopropa[cd]pentalene-4a-carboxylic acid methyl ester; Methyl (2aR,2bR,4aS,4bS)-hexahydro-2-oxo-1H-1-azacyclopropa[cd]pentalene-4a-carboxylate; Bicyclic Lactam Ester; Stereoisomer of CAS 597540-62-0; Chiral Bicyclic Lactam Derivative; Advanced Pharmaceutical Intermediate (API Intermediate)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral HPLC to confirm stereochemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request. We support compliance with cGMP and ISO 9001 standards for pharmaceutical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.