Description

Cyclohexanol, 4-Fluoro-, Acetate, cis- (9Ci) is a fluorinated cyclohexanol derivative, specifically the cis-isomer of the acetate ester of 4-fluorocyclohexanol. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, particularly for introducing fluorinated cyclohexyl motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorinated cyclohexyl structure can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and performance.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex aroma chemicals, where the acetate group and fluorinated ring can modify scent profiles and stability.
• Advanced Polymer Modification: Utilized to introduce fluorinated side chains into polymers, enhancing properties like chemical resistance, thermal stability, and surface characteristics.
• Asymmetric Catalysis & Ligand Development: Functions as a starting material for creating chiral ligands and catalysts used in enantioselective synthesis.

Basic Information

Product Name	Cyclohexanol, 4-Fluoro-, Acetate, cis- (9Ci)
CAS No.	596826-80-1
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	cis-4-Fluorocyclohexyl acetate; (1r,4r)-4-Fluorocyclohexyl acetate; 4-Fluorocyclohexanol acetate, cis-; Acetic acid 4-fluorocyclohexyl ester, cis-; 4-Fluoro-1-cyclohexanol acetate, cis-; (cis)-4-Fluorocyclohexyl ethanoate; 4-Fluorocyclohexyl acetate (cis-isomer); 4-Fluoro-cyclohexanol acetate (cis)
EINECS	Contact for details

Quality Control

Our Cyclohexanol, 4-Fluoro-, Acetate, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (cis-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.