Description

L-Isovaline, n-Hydroxy-, Methyl Ester (9Ci) is a specialized chiral amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial building block for the development of novel bioactive molecules, including peptide mimetics and enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptidomimetics Research: Used to construct non-natural amino acid residues that enhance the stability and bioavailability of peptide-based drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective synthesis to introduce specific stereocenters into complex molecules.
• Biochemical Tool Compound: Useful in studying enzyme mechanisms and receptor-ligand interactions due to its modified amino acid structure.
• Agrochemical Research: Potential intermediate in the development of novel, chiral herbicides or plant growth regulators.
• Material Science: Investigated for incorporation into specialty polymers or coatings that require specific chiral or functional properties.

Basic Information

Product Name	L-Isovaline, n-Hydroxy-, Methyl Ester (9Ci)
CAS No.	596806-69-8
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	Methyl (2S)-2-amino-2-ethyl-3-hydroxypropanoate; L-2-Amino-2-ethyl-3-hydroxypropionic acid methyl ester; (S)-2-Amino-2-ethyl-3-hydroxypropanoic acid methyl ester; n-Hydroxy-L-isovaline methyl ester; Methyl (S)-2-amino-2-ethyl-3-hydroxypropanoate; 3-Hydroxy-L-isovaline methyl ester
EINECS	Contact for details

Quality Control

Our L-Isovaline, n-Hydroxy-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.