Description

Pyridine, 3-(Fluorodimethylsilyl)-5-Nitro- (9Ci) is a specialized organosilicon compound featuring a pyridine backbone functionalized with both a fluorodimethylsilyl group and a nitro substituent. This unique molecular architecture makes it a valuable high-purity building block for advanced material science and pharmaceutical research, where precise functionalization is critical. It is primarily sought by R&D and process development teams in the agrochemical, pharmaceutical, and specialty chemical sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those requiring silicon-fluorine chemistry for enhanced metabolic stability or bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the nitro and fluorosilyl groups can contribute to specific biological activity and environmental persistence profiles.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of specialty polymers, coatings, and silicon-based advanced materials with tailored surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the pyridine nitrogen and silyl groups for metal coordination and support.
• Organic Synthesis Building Block: Provides a versatile handle for further chemical transformations (e.g., reduction of the nitro group, hydrolysis of the silyl group) in complex multi-step synthetic routes.
• Research & Development: A critical reagent for academic and industrial research exploring new reactions in organofluorine and organosilicon chemistry.

Basic Information

Item	Detail
Product Name	Pyridine, 3-(Fluorodimethylsilyl)-5-Nitro- (9Ci)
CAS No.	593287-43-5
Molecular Formula	C7H9FN2O2Si
Molecular Weight	200.25 g/mol
Synonyms	3-[(Fluorodimethylsilyl)]-5-nitropyridine; 5-Nitro-3-(fluorodimethylsilyl)pyridine; 3-Fluorodimethylsilyl-5-nitropyridine; (5-Nitro-3-pyridyl)fluorodimethylsilane; Fluorodimethyl(5-nitro-3-pyridyl)silane; 3-Pyridinesilanol, 5-nitro-, 1,1-dimethyl-1-fluoro- (9CI); Contact for EINECS details.

Quality Control

Our production of Pyridine, 3-(Fluorodimethylsilyl)-5-Nitro- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Isolate from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.