Description

2-Pyridinemethanethiol,α-Methyl-,(Alphas)-(9Ci) is a specialized organosulfur compound featuring a pyridine backbone with a chiral α-methyl thiol substituent. This molecular structure makes it a valuable chiral building block and ligand precursor in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications requiring high stereochemical control. The compound is supplied with full traceability and quality documentation to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and infectious diseases.
• Asymmetric Catalysis: Used as a precursor for the development of novel chiral ligands and catalysts for enantioselective synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new reaction pathways in organometallic and medicinal chemistry.
• Fine Chemical Synthesis: Acts as a building block for creating complex, high-value specialty chemicals with specific stereochemical configurations.
• Material Science: Investigated for potential use in creating functionalized surfaces or polymers where the pyridine-thiol moiety can act as an anchor or modifier.

Basic Information

Product Name	2-Pyridinemethanethiol,α-Methyl-,(Alphas)-(9Ci)
CAS No.	591245-53-3
Molecular Formula	C7H9NS
Molecular Weight	139.22 g/mol
Synonyms	(αS)-α-Methyl-2-pyridinemethanethiol; (S)-1-(Pyridin-2-yl)ethane-1-thiol; α-Methyl-2-pyridinemethanethiol, (αS)-; (S)-(-)-α-Methyl-2-pyridine methanethiol; 2-((1S)-1-Mercaptoethyl)pyridine; (S)-2-(1-Mercaptoethyl)pyridine; (S)-1-Pyridin-2-ylethanethiol
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinemethanethiol,α-Methyl-,(Alphas)-(9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with the highest standards for research chemicals. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment to guarantee reproducible results for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and prolong shelf life. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.