Description

2-Pyridinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-4-Methoxy- is a high-purity, stereochemically defined pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-specific pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where precise molecular architecture is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates, especially in central nervous system (CNS) and analgesic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• Process Chemistry Development: Serves as a standard or starting material for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis methodology and asymmetric catalysis.

Basic Information

Product Name	2-Pyridinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-4-Methoxy-
CAS No.	590373-99-2
Molecular Formula	C14H19N3O2
Molecular Weight	261.32 g/mol
Synonyms	(1S,2R,4R)-N-(7-Azabicyclo[2.2.1]hept-2-yl)-4-methoxypyridine-2-carboxamide; 4-Methoxy-N-[(1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-yl]pyridine-2-carboxamide; (1S,2R,4R)-2-[(4-Methoxypyridine-2-carbonyl)amino]-7-azabicyclo[2.2.1]heptane; 590373-99-2; 4-Methoxy-2-pyridinecarboxylic acid (1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-ylamide
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-4-Methoxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for advanced research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material manufactured under GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storage under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.