Description

2-Pyridinecarboxamide,n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept-3-Yl-4-Methoxy- is a sophisticated chiral organic compound featuring a pyridinecarboxamide moiety linked to a substituted azabicycloheptane core. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate or building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or receptor-specific pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Ligand Synthesis: Serves as a precursor for complex ligands in catalysis or receptor-binding studies.
• Neurological Drug Development: Potential applications in the development of compounds targeting nicotinic acetylcholine receptors or related neurological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring high stereochemical purity and specific molecular frameworks.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	2-Pyridinecarboxamide,n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept-3-Yl-4-Methoxy-
CAS No.	590370-53-9
Molecular Formula	C14H19N3O2
Molecular Weight	261.32 g/mol
Synonyms	4-Methoxy-1-azabicyclo[2.2.1]hept-3-yl-pyridine-2-carboxamide; (1R,3R,4S)-3-[(Pyridine-2-carbonyl)amino]-1-azabicyclo[2.2.1]heptane-4-methyl ether; (1R,3R,4S)-4-Methoxy-1-azabicyclo[2.2.1]hept-3-yl-pyridin-2-yl-methanone; 2-Pyridinecarboxamide, N-[(1R,3R,4S)-4-methoxy-1-azabicyclo[2.2.1]hept-3-yl]-; (1R,3R,4S)-N-(4-Methoxy-1-azabicyclo[2.2.1]hept-3-yl)pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Specifications can be aligned with cGMP guidelines for pharmaceutical development applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original sealed container to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.