Description

3-Amino-5-Bromo-2-Chloropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials who require reliable access to high-quality, well-characterized intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create complex chelating ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the production of specialty polymers, liquid crystals, and electronic chemicals.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects.

Basic Information

Product Name	3-Amino-5-Bromo-2-Chloropyridine
CAS No.	588729-99-1
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	5-Bromo-2-chloro-3-pyridinamine; 2-Chloro-5-bromo-3-aminopyridine; 3-Pyridinamine, 5-bromo-2-chloro-; 5-Bromo-2-chloropyridin-3-amine; 2-Chloro-5-bromopyridin-3-amine; 3-Amino-5-bromo-2-chloropyridine; 5-Bromo-2-chloro-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromo-2-Chloropyridine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality standards are designed to meet the rigorous demands of pharmaceutical and fine chemical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.