Description

6-Indolizinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-(9Ci) is a high-purity, stereochemically defined pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop and scale up production of new therapeutic candidates with enhanced specificity and potency.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• Neurological Drug Research: Used in the synthesis of compounds targeting neurological receptors and pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in the development of robust, scalable synthetic routes for API manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and biological evaluation.

Basic Information

Product Name	6-Indolizinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-(9Ci)
CAS No.	588726-13-0
Molecular Formula	C14H17N3O
Molecular Weight	243.31 g/mol
Synonyms	(1S,2R,4R)-N-(7-Azabicyclo[2.2.1]hept-2-yl)-6-indolizinecarboxamide; (1S,2R,4R)-2-[(6-Indolizinecarbonyl)amino]-7-azabicyclo[2.2.1]heptane; 7-Azabicyclo[2.2.1]heptan-2-amine, N-(6-indolizinecarbonyl)-, (1S,2R,4R)-; 588726-13-0; (1S,2R,4R)-7-Azabicyclo[2.2.1]hept-2-yl 6-indolizinecarboxamide; 6-Indolizinecarboxylic acid, (1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-ylamide
EINECS	Contact for details

Quality Control

Our 6-Indolizinecarboxamide,n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-2-Yl-(9Ci) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We adhere to ICH Q7 guidelines and can provide material with specifications tailored to your project requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is supplied with every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.