Description

Imidazo[1,2-A]Pyridine-6-Carboxamide, n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept- CAS NO 588722-06-9 is a high-purity, chiral organic compound featuring a complex bicyclic structure that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its role as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. This product is essential for research institutions and pharmaceutical manufacturers engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry with custom synthesis and development.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-6-Carboxamide, n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept- CAS NO 588722-06-9
CAS No.	588722-06-9
Molecular Formula	C14H16N4O
Molecular Weight	256.31 g/mol
Synonyms	N-[(1R,3R,4S)-1-Azabicyclo[2.2.1]hept-3-yl]imidazo[1,2-a]pyridine-6-carboxamide; (1R,3R,4S)-N-(Imidazo[1,2-a]pyridin-6-yl)-1-azabicyclo[2.2.1]heptane-3-carboxamide; Imidazo[1,2-a]pyridine-6-carboxylic acid (1R,3R,4S)-1-azabicyclo[2.2.1]hept-3-ylamide; 588722-06-9; Endo-N-(Imidazo[1,2-a]pyridin-6-yl)-1-azabicyclo[2.2.1]heptane-3-carboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications and test results are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.