Description

Methyl 2-(Trifluoromethyl)Isonicotinate CAS NO 588702-68-5 is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl and ester functional groups, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for specialty chemical production.

Basic Information

Product Name	Methyl 2-(Trifluoromethyl)Isonicotinate
CAS No.	588702-68-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	Methyl 2-(trifluoromethyl)pyridine-4-carboxylate; 2-(Trifluoromethyl)isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-trifluoromethylisonicotinate; Isonicotinic acid, 2-(trifluoromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(Trifluoromethyl)Isonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.