Description

2-Bromo-6-(Methylsulfonylmethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine core functionalized with a methylsulfonylmethyl group. This compound matters for its critical role as a versatile building block in modern organic synthesis, enabling the construction of complex molecules with precise structural control. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in medicinal chemistry programs targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides due to its reactive halogen and sulfone functionalities.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Material Development: Used in research for creating organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Bromo-6-(Methylsulfonylmethyl)Pyridine
CAS No.	588689-47-8
Molecular Formula	C8H10BrNO2S
Molecular Weight	264.14 g/mol
Synonyms	2-Bromo-6-(methylsulfonylmethyl)pyridine; 6-(Bromomethyl)-2-(methylsulfonyl)pyridine; Pyridine, 2-bromo-6-[(methylsulfonyl)methyl]-; 2-Bromo-6-(methylsulfonylmethyl)pyridin; 2-Bromo-6-methylsulfonylmethylpyridine; (6-Bromo-2-pyridinyl)methyl methyl sulfone
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Methylsulfonylmethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.