Description

1,4-Dioxa-8-Azaspiro[4.5]Decane,8-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-(9Ci) is a sophisticated spirocyclic compound featuring a benzothiophene core, designed for advanced synthetic applications. This high-value intermediate is critical for researchers and manufacturers requiring precise molecular architecture in complex chemical syntheses. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, serving the needs of the pharmaceutical, agrochemical, and specialty fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for functionalized polymers or advanced organic materials requiring specific spirocyclic or benzothiophene motifs.
• Organic Synthesis: An advanced synthon for academic and industrial research in constructing complex nitrogen- and sulfur-containing heterocycles.
• Chemical Biology: Potential use in creating molecular probes or tool compounds for studying biological pathways and protein interactions.

Basic Information

Product Name	1,4-Dioxa-8-Azaspiro[4.5]Decane,8-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-(9Ci)
CAS No.	588674-14-0
Molecular Formula	C16H15ClFNO3S
Molecular Weight	355.81 g/mol
Synonyms	8-[(3-Chloro-4-fluorobenzo[b]thien-2-yl)carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-[(3-chloro-4-fluorobenzo[b]thien-2-yl)carbonyl]-; 588674-14-0; 3-Chloro-4-fluoro-N-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)benzo[b]thiophene-2-carboxamide; Spirocyclic benzothiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.