Description

1H-Imidazole,1,4-Dimethyl-2-(Trifluoromethyl)-(9Ci) is a specialized fluorinated imidazole derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where enhanced metabolic stability, lipophilicity, or bioavailability is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for functionalized ligands, ionic liquids, and advanced polymers with tailored electronic or surface properties.
• Chemical Research & Development: Employed in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry: A valuable reagent for introducing the CF3-substituted imidazole scaffold, a privileged structure in modern fluoroorganic chemistry.

Basic Information

Product Name	1H-Imidazole,1,4-Dimethyl-2-(Trifluoromethyl)-(9Ci)
CAS No.	586965-41-5
Molecular Formula	C6H7F3N2
Molecular Weight	164.13 g/mol
Synonyms	1,4-Dimethyl-2-(trifluoromethyl)-1H-imidazole; 2-(Trifluoromethyl)-1,4-dimethylimidazole; 1,4-Dimethyl-2-trifluoromethylimidazole; 1H-Imidazole, 1,4-dimethyl-2-(trifluoromethyl)-; 586965-41-5
EINECS	Contact for details

Quality Control

Our 1H-Imidazole,1,4-Dimethyl-2-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.